РОСБИОТЕХ
Bulletin of the Medical Institute of Continuing Education
SURGERY

Original research

УДК 616-002.32

Included in the list of the Higher Attestation Commission
3.1.9. Surgery

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CC BY-NC-ND 4.0

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PREDICTING THE OUTCOMES OF TIBIAL ARTERY REVASCU-LARIZATION IN SEVERE ATHEROSCLEROTIC LESIONS USING LU-MINESCENCE SPECTROSCOPY

A.N. Kosenkovorcid, A.G. Vaganovorcid, A.D. Aslanovorcid, A.T. Edigovorcid

DOI

ABSTRACT

Background. Predicting the outcomes of tibial artery revascularization o in severe atherosclerotic lesions is an urgent challange of angiosurgery.

Purpose. To determine the possibility of predicting the results of arterial recon-struction in severe atherosclerotic lesions of the tibial arteries with trophic defects using luminescent spectroscopy.

Materials and methods. A 14-day prospective study was conducted on 30 pa-tients who were treated in the Department of Vascular Surgery of the Republican Clinical Medical and Surgical Center in Nalchik. In the preoperative period, the in-tensity of luminescence of inflamed tissues was measured in all patients at the level of existing trophic ulcers using laser-induced ultraviolet violet photoluminescence spectroscopy. According to the luminescent signal level, the patients were divided into 2 groups: gGroup 1 — with a signal level in the projection of a ulcerative defect 0.3-0.5 x 105 photons; Group 2 — with a signal level of 0.5-0.7 x105 photons. In addition, subgroup A underwent conservative therapy with alprostadil 40 mcg twice a day intravenously during the entire follow–up period, while subgroup B underwent hybrid surgery with angioplasty of the key artery of the tibia. The size of trophic defects on the lower leg was measured using the “AnalyRan” software.

Results. The healing rate of trophic ulcers healing differed significantly in Group 1 starting from Day 11, with a higher rate in surgically treated patients (p<0.05). In Group 2, the situation was opposite, the statistically significant healing rate of trophic defects in the subgroup with conservative alprostadil therapy exceeded that in subgroup B, from the 9th day of the study (p<0.05). As the wound healing rate increased, the rate of granulation tissue formation also increased, which was in-versely related to the amplitude of the measured tissue luminescence.

Conclusion. In patients with stenoclusive lesion of the lower leg arteries and trophic defects, with an autoluminescence amplitude of 0.3-0.5x105 photons, indi-rect revascularization and conservative treatment is preferable, and with an ampli-tude of 0.5-0.7x105 photons, direct revascularization of the angiosomal artery is preferable.

ABOUT AUTHORS

A.N. Kosenkov Dr.Sci.(Med.), professor

Head of the Department of Surgery of National Institute of Organization of Medical Activity; Moscow, Russia

https://orcid.org/0000-0002-6975-5802

A.G. Vaganov Cand.Sci.(Med.)

Associate Professor of the Department of Hospital Surgery of Kabardino-Balkarian State University; Nalchik, Russia

SPIN-код: 2202-0746 | https://orcid.org/0000-0001-8191-2551

A.D. Aslanov Dr.Sci.(Med.), professor

Head of the Department of Hospital Surgery of Kabardino-Balkarian State University; Nalchik, Russia

https://orcid.org/0000-0002-7051-0917 | SPIN код: 1452-7020

A.T. Edigov

Senior lecturer at the Department of Hospital Surgery of Kabardino-Balkarian State University; Nalchik, Russia

https://orcid.org/0000-0003-3150-3631

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KEYWORDS: critical ischemia of the lower extremities, trophic ulcer, obliterating atherosclerosis, luminescent spectroscopy, "AnalyZer", hybrid surgery on the arteries of the lower extremities

CORRESPONDENCE: Alexey G. Vaganov, e-mail: aleksejvaganov4@gmail.com

FOR CITATIONS: Kosenkov A.N., Vaganov A.G., Aslanov A.D., Edigov A.T. Predictiing the Out-comes of Tibial Artery Revascularization in Severe Atherosclerotic Lesions Using Luminescence Spectroscopy // Bulletin of the Medical Institute of Continuing Edu-cation. — 2025. — Vol. 5, №. 4. P. 64–68. — DOI 10.36107/2782-1714_2025-5-4-64-68.

FUNDING SOURCE: The authors declare no funding for the study.

DECLARATION OF COMPETING INTEREST: The authors declare no apparent or potential conflicts of interest related to the publication of this article.

DATA AVAILABILITY STATEMENT: Data from the current study are available from the corresponding author upon reasonable request.

AUTHOR CONTRIBUTIONS

A.N. Kosenkov — study concept and design, data collection and processing, data analysis, editing.

A.G. Vaganov — article concept, text writing, literature review, statistical processing..

A.D. Aslanov — collection and statistical processing of the data, approval of the final version of the article..

A.T. Edigov — literature review, data collection and statistical processing.

INFORMED CONSENT FOR PUBLICATION: authors received written consent from patients for publication of medical data and photographs.

COMPLIANCE WITH ETHICAL PRINCIPLES: The study conducted complies with the standards of the Declaration of Helsinki (Declaration Helsinki) as amended in 2024. The study protocol's compliance with ethical principles was confirmed by the Local Ethics Committee Medical Institute of Continuing Education, Russian Biotechnology University (ROSBIOTECH) on (Volokolamskoe highway, 11, Moscow, Russia), protocol № 13/8-4 from 09.12.2025 г.