UROLOGY AND ANDROLOGY

Original research

УДК 616.65-002-008.6.

Included in the list of the Higher Attestation Commission
3.1.13. Urology and andrology

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FEATURES OF THE POSTOPERATIVE PERIOD IN PATIENTS UNDERGOING ENDOUROLOGICAL INTERVENTIONS FOR PROSTATIC HYPERPLASIA

Kh. N.Najmiddinovorcid, A.A. Gritskevichorcid, D.M. Monakovorcid, T.P. Baitmanorcid, A.G. Kochetovorcid, A.B. Bogdanovorcid

DOI

ABSTRACT

Background. Endourological interventions are one of the main methods of treating prostatic hyperplasia, allowing to quickly eliminate obstructive symptoms. However, in some patients, surgery not only fails to improve their condition, but there may also be an increase in the symptoms of the disease or even the appearance of new clinical manifestations, which requires an analysis of the features of the postoperative period in this category of patients.

Materials and methods. The analysis of the course of the postoperative period for 90 days was carried out in 130 patients who underwent various endourological interventions. Anthropometric data, concomitant pathology of patients, prostate volume and amount of residual urine, uroflowmetric parameters, severity of symptoms assessed using the IPSS, QoL, and OAB questionnaires, as well as the type of patient's attitude to the disease (using the TOBOL technique) were analyzed. The initial data were evaluated and the results of the examination immediately after discharge, 2 weeks, 1, 2 and 3 months after surgery.

Results. Within 90 days, there was a steady tendency to improve the symptoms of the disease, reflected in reduced mean scores on the IPSS, QoL, and OAB scales, increased average and maximum flow rate of urine, and normalization of the amount of residual urine. Nevertheless, 26.2% of patients were not satisfied with the results of treatment. Predictors of such outcomes could not be identified. Discussion. By the end of 3 months of the postoperative period, patients who underwent endourological interventions for prostatic hyperplasia retained moderate symptoms, which may be due to ongoing reparative processes in surgery.

Conclusion. Endourological interventions can quickly and effectively eliminate the symptoms of the lower urinary tract in patients with prostatic hyperplasia, however, 3 months after surgery, patients may experience moderate symptoms, and a quarter of them are not satisfied with the results of treatment. Further studies are needed to evaluate the results of treatment in the long-term postoperative period.

ABOUT AUTHORS

Kh. N.Najmiddinov

Urologist, City polyclinic No. 219; Moscow, Russia

Postgraduate student of the Department of Urology and Operative Nephrology with a course in Oncourology, Peoples' Friendship University of Russia named after Patrice Lumumba; Moscow, Russia

https://orcid.org/0009-0006-2227-2850

A.A. Gritskevich Dr.Sci.(Med.)

Professor of the Department of Urology and Operative Nephrology with a course in Oncourology of Peoples' Friendship University of Russia named after Patrice Lumumba; Moscow, Russia

Head of the Department of Oncological Urology and Urology of National Medical Research Center of Surgery named after A.V. Vishnevsky; Moscow, Russia

РИНЦ AuthorID:816947 | https://orcid.org/0000-0002-5160-925x

D.M. Monakov Cand.Sci.(Med.)

Associate Professor of the Department of Urology and Operative Nephrology with a course in Oncourology of Peoples' Friendship University of Russia named after Patrice Lumumba; Moscow, Russia

Senior researcher in oncological urology and urology of National Medical Research Center of Surgery named after A.V. Vishnevsky; Moscow, Russia

РИНЦ Аuthor ID 995385 | https://orcid.org/0000-0002-9676-1802

T.P. Baitman Cand.Sci.(Med.)

Assistant Professor of the Department of Urology and Operative Nephrology with a course in Oncourology of Peoples' Friendship University of Russia named after Patrice Lumumba; Moscow, Russia

Research fellow in oncological urology and urology of National Medical Research Center of Surgery named after A.V. Vishnevsky; Moscow, Russia

РИНЦ Аuthor ID 1064032 | https://orcid.org/0000-0002-3646-1664

A.G. Kochetov Dr.Sci.(Med.)

Head of the Urology Center of National Medical Research Center, High Medical Technologies, Central Military Clinical Hospital named after A.A. Vishnevsky; Krasnogorsk, Russia

Head of the Department of Urology of Medical Institute of Continuing Education, Russian Biotechnological University (ROSBIOTECH); Moscow, Russia

РИНЦ AuthorID:354654 | https://orcid.org/0000-0003-3151-5181

A.B. Bogdanov Cand.Sci.(Med.)

Urologist of the urology department of Moscow Multidisciplinary Scientific and Clinical Center named after S.P. Botkin; Moscow, Russia

Associate Professor of the Department of Urology and Surgical Andrology of Russian Medical Academy of Continuous Medical Education; Moscow, Russia

РИНЦ Author ID 742456 | https://orcid.org/0000-0001-5347-8364

LITERATURE

  1. Аполихин О.И., Сивков А.В., Комарова В.А., Никушина А.А. Болезни предстательной железы в Российской Федерации: статистические данные 2008–2017 гг. // Экспериментальная и клиническая урология. — 2019. — № 2. — С. 4–13. — DOI: 10.29188/2222-8543-2019-11-2-4-12.
  2. Доброкачественная гиперплазия предстательной железы: клинические рекомендации. — Министерство здравоохранения Российской Федерации, 2024. — 95 с. — URL: https://cr.minzdrav.gov.ru/preview-cr/6_2 (дата обращения: 01.08.2025).
  3. Sandhu JS, Bixler BR, Dahm P. et al. Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia (BPH): AUA Guideline Amendment 2023 // J Urol. — 2024. — Vol. 211, Т. 1. — P. 11–19. — DOI: 10.1097/JU.0000000000003698.
  4. Sciacqua LV, Vanzulli A, Di Meo R. et al. Minimally Invasive Treatment in Benign Prostatic Hyperplasia (BPH) // Tech Cancer Res Treat. — 2023. — Vol. 22. — Art. no. 15330338231155000. — DOI: 10.1177/15330338231155000.
  5. Крупин А.В., Крупин В.Н., Севрюков Ф.А. Симптомы нижних мочевыводящих путей у мужчин после операций по поводу доброкачественной гиперплазии простаты // Урологические ведомости. — 2024. — Т. 14, № 3. — С. 293–301. — DOI: 10.17816/uroved633196.
  6. Rieken M, de Nunzio C, Cornu JN. et al. Medical Treatment Incidence and Persistence After Surgical Relief of Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Obstruction: A Critical Analysis of the Literature // Eur Urol Focus. — 2024. — Vol. 10, Iss. 3. — P. 421–431. — DOI: 10.1016/j.euf.2023.08.013.
  7. Симанов Р.Н., Амдий Р.Э., Аль-Шукри С.Х. и др. Расстройства мочеиспускания и качество жизни у больных ДГПЖ после трансуретральной резекции предстательной железы // Экспериментальная и клиническая урология. — 2023. — № 1. — С. 116–121.
  8. Гиоргобиани Т.Г., Амдий Р.Э. Диагностика и лечение расстройств мочеиспускания после хирургического лечения доброкачественной гиперплазии предстательной железы // Урологические ведомости. — 2016. — Т. 6, доп. вып. — С. 47–48.
  9. Попов С.В., Орлов И.Н., Цой А.В и др. Стеноз шейки мочевого пузыря после хирургического лечения пациентов с доброкачественной гиперплазией предстательной железы. Эпидемиология. Современные возможности лечения // Экспериментальная и клиническая урология. — 2021. — Т. 14, № 1. — С. 100–107. — DOI: 10.29188/2222-8543-2021-14-1-100-107.
  10. Garza-Montúfar ME, Cobos-Aguilar H, Treviño-Baez JD. et al. Factors Associated With Urethral and Bladder Neck Stricture After Transurethral Resection of the Prostate // J Endourol. — 2021. — Vol. 35, Т. 9. — P. 1400–1404.
  11. Волков С.Н., Пушкарь Д.Ю., Колонтарев К.Б. и др. Выраженность симптомов нижних мочевых путей в послеоперационном периоде как фактор выбора подхода к хирургическому лечению гиперплазии простаты больших размеров: гольмиевая энуклеация предстательной железы и лапароскопическая позадилонная аденомэктомия // Вестник урологии. — 2024. — Т. 12, № 2. — С. 5–14. — DOI: 10.21886/2308-6424-2024-12-2-5-14.
  12. Franco JVA, Jung JH, Imamura M. et al. Minimally Invasive Treatments for Benign Prostatic Hyperplasia: A Cochrane Network Meta-Analysis // BJU Int. — 2022. — Vol. 130, Т. 2. — P. 142–156. — DOI: 10.1111/bju.15653.
  13. Костенков Н.Ю., Невирович Е.С., Горелик С.Г. и др. Сравнительная оценка интра- и раннего послеоперационного периода у больных пожилого и старческого возраста после различных методов хирургического лечения доброкачественной гиперплазии предстательной железы больших размеров // Consilium Medicum. — 2022. — Т. 24, № 7. — С. 447–450. — DOI: 10.26442/20751753.2022.7.201876. — EDN AYNMLQ.
  14. Bucca B, Gozzi C, Gobbi LM. et al. The Dark Side of Transurethral Access for LUTS/BPH Surgery: A Narrative Review // Asian J Androl. — 2025. — Online ahead of print. — DOI: 10.4103/aja202523.

KEYWORDS: prostatic hyperplasia, treatment, transurethral resection, laser enucleation, ablation, lower urinary tract symptoms

CORRESPONDENCE: Khayem N. Najmiddinov, e-mail: hayom-n@mail.ru

FOR CITATIONS: Najmiddinov Kh.N., Gritskevich A.A., Monakov D.M. [at al.] Features of the Postoperative Period in Patients Undergoing Endourological Interventions for Prostatic Hyperplasia // Bulletin of the Medical Institute of Continuing Education. — 2025. — V. 5, No. 4. — S. 69–74. — DOI 10.36107/2782-1714_2025-5-4-69-74.

FUNDING SOURCE: The authors declare no funding for the study.

DECLARATION OF COMPETING INTEREST: The authors declare no apparent or potential conflicts of interest related to the publication of this article.

DATA AVAILABILITY STATEMENT: Data from the current study are available from the corresponding author upon reasonable request.

AUTHOR CONTRIBUTIONS

Х.Н. Наджмиддинов — сбор и обработка данных, поиск публикаций по теме исследования, написание текста статьи.

А.А. Грицкевич — дизайн исследования, общее руководство исследованием.

Д.М. Монаков — обработка и анализ данных, поиск и анализ публикаций по теме исследования, написание текста.

Т. П. Байтман — поиск публикаций по теме исследования.

А. Г. Кочетов — дизайн исследования, написание текста.

А. Б. Богданов — сбор и обработка данных.

INFORMED CONSENT FOR PUBLICATION: authors received written consent from patients for publication of medical data and photographs.

COMPLIANCE WITH ETHICAL PRINCIPLES: The study conducted complies with the standards of the Declaration of Helsinki (Declaration Helsinki) as amended in 2024. The study protocol's compliance with ethical principles was confirmed by the Local Ethics Committee Medical Institute of Continuing Education, Russian Biotechnology University (ROSBIOTECH) on (Volokolamskoe highway, 11, Moscow, Russia), protocol № 12/7-4 from 28 октября 2025.